Celgene signs Concert pact, apremilast impresses for PsA

8 05 2013

New Drug Approvals

Apremilast is an orally available small molecule inhibitor of PDE4 being developed byCelgene for ankylosing spondylitis, psoriasis, and psoriatic arthritis.[1][2] 

Celgene signs Concert pact, apremilast impresses for PsA

Celgene Corp has entered into a collaboration with Concert Pharmaceuticals which will focus on developing deuterium-modified compounds targeting cancer and inflammation. ………..read all at

http://www.pharmatimes.com/Article/13-05-07/Celgene_signs_Concert_pact_apremilast_impresses_for_PsA.aspx

The drug is currently in phase III trials for the three indications. Apremilast, an anti-inflammatory drug, specifically inhibits phosphodiesterase 4. In general the drug works on an intra-cellular basis to moderate proinflammatory and anti-inflammatory mediator production.

 

Apremilast is being tested for its efficacy in treating “psoriasis, psoriatic arthritis and other chronic inflammatory diseases such as ankylosing spondylitis, Behcet’s disease, and rheutmatoid arthritis.”

 

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Syntheticnature

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pharmupdates.wordpress.com/

News and articles on the Pharmaceutical Industry

Combinatorics and more

Gil Kalai's blog

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Seven Spheres

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Chemtips

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